Virus-Like Particles in Human Leukemic Cells — II

Avian lymphoid leukosis: Virus-like particles in kidney Cells

avian lymphoid leukosis: virus-like particles in kidney cells

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Sensitivity of Human Leukemic Cells to Carvedilol

Background and Objective: Carvedilol, a non-specific β-blocker, has been used for treatment of hypertension, stroke and congestive heart failure. The therapeutic effects of β blockers in cancer patients have been shown. Carvedilol has considerable anti-inflammatory, anti-tumor and anti-angiogenic properties. In this study, the effects of carvedilol on proliferation of human U937 and Molt-4 leuk...

Primate RNA tumor virus-like DNA synthesized endogenously by RNA-dependent DNA polymerase in virus-like particles from fresh human acute leukemic blood cells.

A particle of discrete biochemical composition was purified from fresh, unfrozen peripheral blood leukocytes of human patients with acute myeloblastic leukemia. This particle endogenously synthesized DNA by use of an RNA primer and template. About half of the DNA sequences synthesized in the presence of actinomycin D hybridized to RNA isolated from type-C sarcoma viruses of primates or mice; lo...

Virus-like particles in association with L strain cells.

in two of the three sublines virus-like particles of type C were present within cytoplasmic vacuoles and outside the cells close to the cell surface. The particles formed by a budding process at the ceil membrane. Similar particles were observed in pellets prepared from the medium in which the cells had been grown, and in cells of tumors produced in C3H mice by inoculation of the cultured cells...